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Progress in the Application of Nano- and Micro-based Drug Delivery Systems in Pulmonary Drug Delivery

Announcing a new article publication for BIO Integration journal. In this article the authors Rejoice Thubelihle Ndebele, Qing Yao, Yan-Nan Shi, Yuan-Yuan Zhai, He-Lin Xu, Cui-Tao Lu and Ying-Zheng Zhao from Wenzhou Medical University, Wenzhou, China discuss progress in the application of nano- and micro-based drug delivery systems in pulmonary drug delivery.

Nanotechnology is associated with the development of particles in the nano-size range that can be used in a wide range of applications in the medical field. It has gained more importance in the pharmaceutical research field particularly in drug delivery, as it results in enhanced therapeutic drug performance, improved drug solubility, targeted drug delivery to the specific sites, minimized side effects, and prolonged drug retention time in the targeted site.

To date, the application of nanotechnology continues to offer several benefits in the treatment of various chronic diseases and results in remarkable improvements in treatment outcomes. The use of nano-based delivery systems such as liposomes, micelles, and nanoparticles in pulmonary drug delivery have shown to be a promising strategy in achieving drug deposition and maintained controlled drug release in the lungs. They have been widely used to minimize the risks of drug toxicity in vivo.

The authors of this article review recent advances in the application of nano- and micro-based delivery systems in pulmonary drug delivery for the treatment of various pulmonary diseases, such as lung cancer, asthma, and chronic obstructive pulmonary disease. Limitations in the application of these drug delivery systems and some key strategies in improving their formulation properties to overcome challenges encountered in drug delivery are also discussed.

Article reference: Rejoice Thubelihle Ndebele, Qing Yao, Yan-Nan Shi, Yuan-Yuan Zhai, He-Lin Xu, Cui-Tao Lu and Ying-Zheng Zhao, Progress in the Application of Nano- and Micro-based Drug Delivery Systems in Pulmonary Drug Delivery. BIO Integration, 2021, https://doi.org/10.15212/bioi-2021-0028

BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine.

As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

BIOI is now open for submissions; articles can be submitted online at:

https://mc04.manuscriptcentral.com/bioi

Please visit www.bio-integration.org to learn more about the journal.

Editorial Board: https://bio-integration.org/editorial-board/

Please visit www.bio-integration.org to learn more about the journal.

Editorial Board: https://bio-integration.org/editorial-board/

BIOI is available on the IngentaConnect platform (https://www.ingentaconnect.com/content/cscript/bioi) and at the BIO Integration website (www.bio-integration.org).

Submissions may be made using ScholarOne (https://mc04.manuscriptcentral.com/bioi).

There are no author submission or article processing fees.

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ISSN 2712-0074

eISSN 2712-0082

Keywords: Nanotechnology, Pulmonary Drug Delivery, Nanoparticles, Liposomes, Micelles, Controlled Release