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Effects of Vitamin D Supplementation During Pregnancy on Preterm Birth Risk and Maternal-Neonatal Outcomes: A Systematic Review and Meta-Analysis of 38 Randomized Controlled Trials
Announcing a new article publication in BIO Integration. Preterm birth complications are among leading causes of mortality in neonates and children under 5 years of age worldwide. The association between…
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Large-Scale Chemical Space Exploration Identifies DE19725241 as a Candidate Fat Mass and Obesity-Associated Protein-Targeting Compound with Selective Activity in Pancreatic Cancer Cells
Announcing a new article publication in BIO Integration. Fat mass and obesity-associated protein (FTO), an epitranscriptomic regulator, has been implicated in cancer progression and immune regulation but the therapeutic relevance…
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Functional Hydrogels Based on Bioactive Polysaccharides from Traditional Chinese Medicine: Advanced Biomaterial Strategies for Skin Wound Healing
Announcing a new article publication in BIO Integration. Skin wound healing, especially in chronic non-healing conditions, such as diabetic foot ulcers and infected wounds, remains a formidable clinical challenge due…
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Cell Death Analysis: A Comprehensive R Package for Multi-pathway Cell Death Analysis in Transcriptomic Data
Announcing a new article publication in BIO Integration. The authors of this article developed CellDeathAnalysis (v0.4.0), an R package providing a unified framework for analyzing 14 cell death pathways in…
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From Nociception to Regeneration: Temporal Reprogramming of Sensory Neurons in Skeletal Healing
Announcing a new article publication in BIO Integration. Skeletal healing is constrained by a long-standing paradox. Specifically, analgesia is clinically essential, yet neural signaling is biologically required for effective repair.…
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Combining Insulin Resistance and Renal Function to Predict Cardiovascular Events: A Multicenter Cohort Study
Announcing a new article publication in BIO Integration. Insulin resistance (IR) and chronic kidney disease (CKD) are independent risk factors for cardiovascular disease (CVD). The triglyceride-glucose (TyG) index is recognized…
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Novel Metabolomic Biomarkers for Latent Tuberculosis Infection: A Plasma-based Untargeted Metabolomics Approach Using Mass Spectrometry
Announcing a new article publication in BIO Integration. Latent tuberculosis infection (LTBI) is difficult to diagnose due to the lack of a definitive gold standard. This study aimed to explore…
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Lactic acid and Lactylation in the Progression of Pulmonary Fibrosis
Announcing a new article publication in BIO Integration. Pulmonary fibrosis (PF) is a progressive and irreversible interstitial lung disease that is characterized by destruction of alveolar architecture, excessive proliferation of…