Non-Invasive Physical Stimulation to Modulate the Tumor Microenvironment: Unveiling a New Frontier in Cancer Therapy

Announcing a new article publication for BIO Integration journal. The tumor microenvironment (TME) has a crucial role in tumor development, metastasis, and recurrence.

The chaotic and complex physical structure of the TME not only limits drug delivery but also contributes to the development of resistance to immunotherapy. Breaking the physical barrier limitation of the TME could further optimize the existing tumor treatment protocols. Physical stimulation, such as ionizing radiation, light, electricity, magnetic field, and ultrasound, modulate the TME by altering tumor vasculature, remodeling the extracellular matrix, and activating immune responses to achieve the goal of adjuvant to other tumor therapeutic approaches. In addition to adjuvant chemotherapy and immunotherapy, these physical stimulations also enhance the efficacy of other physical treatments for cancer.

The authors of this article discuss the structural characteristics of TME, focus on the modulation of TME by different physical stimulations and analyse the adjuvant effects of these stimulations on other tumor therapies.

Read More: https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0012

BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine. As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

BIOI is now open for submissions; articles can be submitted online at: https://mc04.manuscriptcentral.com/bioi

There are no author submission or article processing fees.

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ISSN 2712-0074

eISSN 2712-0082

Zhili Guo, Phei Er Saw and Sangyong Jon. Non-Invasive Physical Stimulation to Modulate the Tumor Microenvironment: Unveiling a New Frontier in Cancer Therapy. BIOI. 2024. Vol. 5(1). DOI: 10.15212/bioi-2024-0012