Archive / Vol 6, No 1

Mini Reviews

Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment
Mohsina Patwekar, Faheem Patwekar, J. Pavan Kumar, P. Dharani Prasad, Nazia Malik, A. Venkata Badarinath, Prashanth Parupathi, Konatham Teja Kumar Reddy, Selvaraja Elumalai and Zainul Abedeen Ab Samad
Article Category: Mini Review | Pages: 1–20 | Published online: January 28 2025
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Advances in Gene Therapy for Neurologic Disorders: An Overview
Pallavi Chand, K. Trideva Sastri, Ashish Singh Chauhan, Souvik Chakraborty and Vikash Jakhmola
Article Category: Mini Review | Pages: 1–17 | Published online: February 5 2025
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Application of Music Therapy in Stroke Rehabilitation: A Research Review
Ke Wu, Chenxi Li, Sike Zhu, Jiajia Zhuang, Ruogu Chen, Xiuhui Ji, Yanjin Wu and Maowei Chen
Article Category: Mini Review | Pages: 1–20 | Published online: July 2 2025
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Brief Reports

Specific Activity of Lactate Dehydrogenase in Muscle and Liver Tissues of Rats Exposed to Intermittent Hypobaric Hypoxia
Syarifah Dewi, Adiba Nur Ashri Ramadhani, Khoiriyyah Amalia Az-zahra and Wardaya Wardaya
Article Category: Brief Report | Pages: 1–6 | Published online: January 31 2025
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Anticancer Efficacy of 5-Fluorouracil-Loaded Chitin Nanohydrogel in Enhanced Skin Cancer Therapy
Yuvraj D. Dange, Vijay R. Salunkhe, Sandip M. Honmane and Pradnya S. Marale
Article Category: Brief Report | Pages: 1–11 | Published online: July 7 2025
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Low-intensity Pulsed Ultrasound Enhances NK Cell Adoptive Therapy by Modulating the Wnt/β-catenin Signaling Pathway
Renjie Feng, Ao Gu, Gökhan Zengin and Meng Du
Article Category: Brief Report | Pages: 1–8 | Published online: July 15 2025
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Original Articles

Lopinavir and Ritonavir have High Affinity Toward the SARS-CoV-2 S-protein Receptor-binding Domain Sequenced in Brazil
Aline Diogo Marinho, Helyson Lucas Bezerra Braz, João Alison de Moraes Silveira, Danilo Galvão Rocha, Roberta Jeane Bezerra Jorge and Geanne Matos de Andrade
Article Category: Original Article | Pages: 1–10 | Published online: January 31 2025
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Novel CAR-T Cells Specifically Targeting Nectin4 Exhibit Effective Anti-Tumor Efficacy in Bladder Cancer Cell Lines
Jinping Niu, Guodi Liu, Sai Zhang, Chengnan Xu, Ziwen Xu, Xingyuan Ma, Xiaoli Tian and Wenyun Zheng
Article Category: Original Article | Pages: 1–11 | Published online: April 28 2025
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Effects of the Intestinal Microbiome and Metabolites on Neoadjuvant Chemotherapy Efficacy in Breast Cancer
Jingyue Fu, Hongxin Lin, Shuaikang Li, Xingying Yu, Yufan Jin, Jie Mei, Yichao Zhu and Tiansong Xia
Article Category: Original Article | Pages: 1–14 | Published online: July 9 2025
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Multiscale End-point Screening with Extended Tight-binding Hamiltonians
Xiaohui Wang, Sai Li, Zuoyuan Zhang, Linqiong Qiu and Zhaoxi Sun
Article Category: Original Article | Pages: 1–11 | Published online: July 23 2025
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IL2RB and TUBA1B are Potential Targets of Music Therapy for Alzheimer’s Disease and Cognitive Impairment
Ke Wu, Jianling Liu, Yusheng Su, Jiansheng Yang, Jianzhong Xiao, Jia Lina, Zhengzhou Chen, Xianjun Li, Yunshen Ge, Wei Luo, Zhong He, Genbin Huang, Yanjin Wu, Chengwan Shen, Haojun Shi, John H. Zhang, Bin Huang, Maowei Chen and Yisheng Chen
Article Category: Original Article | Pages: 1–17 | Published online: September 2 2025
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Understanding Vascular Toxicity of Indigo Naturalis in Anti-Inflammatory Applications: Mendelian Randomization and Co-localization Study
Jie Liu, Chengjian Liu, Haitao Xiao and Zhiping Xu
Article Category: Original Article | Pages: 1–11 | Published online: December 19 2025
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Ultrasound-Trained Artificial Intelligence for Postmenopausal Adnexal Lesion Characterization: A Multicenter Diagnostic Accuracy Study
Manli Wu, Jiawei Wu, Ying Wang, Wenjun Zhang, Jiang Zhu, Liyi You, Yun Wu, Na Di, Wenkai Li, Qinfeng Kong, Biyun Sun, Guoyi Zhou, Jiahao Luo, Yutong Li, Sheng Zhao, Xin Zhou and Xinling Zhang
Article Category: Original Article | Pages: 1–12 | Published online: December 24 2025
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Editorial

Welcome to BIO Integration 2025: Embracing a New Era in Biomaterials and Clinical Therapy
Zhiwen Luo, Chaozong Liu, Pintong Huang and Zhiyi Chen
Article Category: Editorial | Pages: 1–3 | Published online: March 12 2025
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Clinicians and Scientists: Turn to AI, Not into AI
Guiping Lin, Xiuying Cui, Manting Xie and Phei Er Saw
Article Category: Editorial | Pages: 1–5 | Published online: December 8 2025
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Reviews

Lipid-based Nanoparticles: Strategy for Targeted Cancer Therapy
Ashish Singh Chauhan, Pallavi Chand and Tarun Parashar
Article Category: Review | Pages: 1–23 | Published online: April 4 2025
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Targeted Drug Delivery System for Pulmonary Fibrosis: Design and Development of Biomaterials
Jinsha Liu, Zifeng Pan, Arshma Khan and Haoguang Li
Article Category: Review | Pages: 1–23 | Published online: April 12 2025
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Recent Developments in Diabetes Management: Exploring Receptors, Pathways, and Compounds
Pallavi Pandey, Vikash Jakhmola, Supriyo Saha and Anand Gaurav
Article Category: Review | Pages: 1–28 | Published online: May 7 2025
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Combating Multi-drug Resistant Mycobacterium Species by Efflux Pump Inhibitors: Contemporary Trends
Gautam Kumar, Priya Mondal, Amit Kadam, Isha Dhamija, Ravindra Pal Singh, Deepak Nathiya and Sandeep Kumar
Article Category: Review | Pages: 1–32 | Published online: June 2 2025
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Advances in Drug Delivery Systems for Osteochondral Tissue Regeneration
Jun Shang, Jianping Zhang, Linhong Liu, Wenjuan Kou, Pingping Zhang, Guangwei Sun, Huishuang Zhou, Weihan Shi, Yaning Zhang, Chaozong Liu and Bin Li
Article Category: Review | Pages: 1–28 | Published online: July 30 2025
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Mechanoregulation of Cell Fate by Low-intensity Pulsed Ultrasound: Mechanisms and Advances in Regenerative Medicine
Lingling Lei, Qing Zhang, Meng Du and Li Li
Article Category: Review | Pages: 1–18 | Published online: July 30 2025
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Mechanistic Insights and Therapeutic Potential of Quercetin in Neuroprotection: A Comprehensive Review of Pathways and Clinical Perspectives
Ishita Debnath, Suman Ghosh, Sajal Kumar Jha, Sobhanjan Bhunia, Aditi Nayak, Souvik Basak, Sumit Nandi and Soumik Bhattacharjee
Article Category: Review | Pages: 1–31 | Published online: August 18 2025
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Exogenous Extracellular Vesicles as Emerging Platforms in Translational Medicine
Muran Bai, Zhongshi Li, Tianren Shi, Xiangling Li, Jia Li, Jian Ma, Lei Huang and Zhijin Fan
Article Category: Review | Pages: 1–25 | Published online: September 19 2025
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Harnessing Cell Membrane-Derived Nanovesicles for Enhanced Nanoprobes in Multimodal Imaging: Progress and Perspectives
Lingling Lei, Meng Du, Jianjian Zhang and Yuguang Mu
Article Category: Review | Pages: 1–17 | Published online: October 17 2025
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Recent Advances and Future Prospects in Wearable Flexible Sensors for Motion Monitoring
Zhengyang Chang, Jianpeng Gao, Xiao Liu, Zijian Li, Jiabing Zhang, Jing Zhang, Licheng Zhang, Tianqi Wang, Hufei Wang and Ming Li
Article Category: Review | Pages: 1–17 | Published online: October 22 2025
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Combined Ultrasound and Microneedle for Enhanced Transdermal Delivery: Synergistic Mechanisms and Therapeutic Advances
Lingling Lei, Wangrui Peng, Jianfeng Cai and Chao Lu
Article Category: Review | Pages: 1–21 | Published online: November 18 2025
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Artificial Intelligence in Pediatric Ultrasound: An Update and Future Applications
Chenke Kuang, Zekun Jiang, Yang Wang, Aiqing Fang, Heng Zhang, Haipeng Liu and Zhewei Ye
Article Category: Review | Pages: 1–21 | Published online: November 20 2025
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Advances in the Application of Living Cells in Tumor Radiosensitization
Haonan Xu, Renjie Feng and Hengrui Liu
Article Category: Review | Pages: 1–16 | Published online: December 4 2025
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Commentaries

Vitcylation of Lysine: The Novel Mechanism of Vitamin C in Tumor Treatment
Jiatong Li, Ao Gu, Nannan Tang, Jin-Wei Zhou, Chen Li, Gokhan Zengin and Meng-Yao Li
Article Category: Commentary | Pages: 1–6 | Published online: May 21 2025
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MicroRNAs in Liver Fibrosis: Unraveling Intercellular Crosstalk and the Regulatory Functions of MicroRNA-223
Chinnatam Phetkong and Chaiyaboot Ariyachet
Article Category: Commentary | Pages: 1–6 | Published online: June 18 2025
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Asymmetric Cell Division as a Mechanistic Contributor to Cancer with a Focus on Glioblastoma
Rebecca Golin, Genia Bekker and Hengrui Liu
Article Category: Commentary | Pages: 1–8 | Published online: July 4 2025
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Armored and Cold Tumors: A Refractory Subset of Solid Cancer
Rui Xu, Kai Yang, Yun Cai, Jabed Iqbal, Yichao Zhu, Yan Zhang and Jie Mei
Article Category: Commentary | Pages: 1–6 | Published online: September 8 2025
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Role of Photofunctionalization in Orthopedic Customized Implants
Yang Liu, Pinxue Li, Xiangliang Li, Huimin Kong and Chuan Yin
Article Category: Commentary | Pages: 1–6 | Published online: September 8 2025
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Editorial Commentaries

Conversational AI in Medicine: Redefining Diagnostics with AMIE
Ziyang Lin, Yawei Du, Wu Yang, Yu Qian and Junjie Li
Article Category: Editorial Commentary | Pages: 1–3 | Published online: July 24 2025
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A Strategy for Antigen Amplification via Nanozyme-Catalyzed Proximity Labeling
Yinghui Men, Ke Shao and Yingcheng Wu
Article Category: Editorial Commentary | Pages: 1–2 | Published online: September 15 2025
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A Promising Path Forward in Obesity Pharmacotherapy: Ecnoglutide and the Evolution of GLP-1R Agonist Design
Liangbin Zhou, Pingyu Jin, Dongze Wu and Xiangdong Ye
Article Category: Editorial Commentary | Pages: 1–4 | Published online: December 31 2025
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Research Letter

WukongBot: A Brain-Spine Interface Proof of Concept Based on Non-Invasive Brain-Computer Interface for Spinal Cord Injury in a Monkey
Lifen Mo, Long Chen, Yichang Liao, Yihang Ren, Binbin Li, Zhenhua Song, Wen Xu, Fengyan Liang, Qianqian Fan, Xiaodi Han and Ming Yin
Article Category: Research Letter | Pages: 1–3 | Published online: November 11 2025
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