Nanofibers for Drug Delivery: Design and Fabrication Strategies

Announcing a new article publication for BIO Integration journal. Nanotechnology is an emerging field with substantial scientific and economic potential globally. Researchers are increasingly focusing on creating nanomaterials for diverse applications. This review article explores the potential of drug-loaded nanofibers for drug delivery and describes their production methods, including centrifugal jet spinning, plasma-induced synthesis, solution blow spinning (SBS), pressure spinning, and electrospinning. Nanofibers, owing to their extensive surface area relative to their volume, are believed to enhance interactions with target substances and therefore are valuable in numerous applications. This article provides a thorough exploration of fabrication techniques, encompassing fundamental concepts, methods, and material aspects and provides perspectives on the variables affecting the production and application of nanofibers, such as electrospinning parameters (including electric field intensity, needle size, flow rate, and distance between the needle and collector), solution characteristics (such as polymer concentration, solvent type, conductivity, and viscosity), and environmental factors (such as temperature and humidity). Additionally, an extensive compilation of patents related to nanofiber-based drug delivery systems is presented, showcasing innovations and advancements in the field. Current clinical trials involving nanofiber technologies are also examined, providing insights into their therapeutic potential and translational prospects. An overview of nanofiber drug delivery systems is presented including identifying future opportunities and challenges in their development and application.

Read full article at Scienceopen: https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0023

BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine. As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

BIOI is now open for submissions; articles can be submitted online at: https://mc04.manuscriptcentral.com/bioi

There are no author submission or article processing fees.

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ISSN 2712-0074

eISSN 2712-0082

Nisha Kalayil, Aarati Anil Budar and Roshan Kalulal Dave. Nanofibers for Drug Delivery: Design and Fabrication Strategies. BIOI. 2024. Vol. 5(1). DOI: 10.15212/bioi-2024-0023