Formulation and Development of Tara Gum-mediated Tablets for Delivery of Anticancer Drugs

Announcing a new article publication for BIO Integration journal.  Natural polysaccharide tara gum (TG) has been investigated for several biological uses. This article discusses the administration of imatinib, an anticancer model medication, via TG.

Imatinib-modified release tablets were developed using a direct compression method with different concentrations of TG and other excipients. Compressed tablets were evaluated for physicochemical properties.

All formulations had an in vitro disintegration time ranging from 10–23 min. Among the formulations, F6 exhibited excellent extended-release behaviour with 72% release over 12 h. TG tablets were rich in phytoconstituents, including saponins, tannins, phenolics, flavonoids, carbohydrates, proteins, and amino acids.

TG has potential in the drug delivery application of anticancer medications as a rate-retarding polymer.

Read More: https://www.scienceopen.com/hosted-document?doi=10.15212/bioi-2024-0040

BIO Integration is fully open access journal which will allow for the rapid dissemination of multidisciplinary views driving the progress of modern medicine. As part of its mandate to help bring interesting work and knowledge from around the world to a wider audience, BIOI will actively support authors through open access publishing and through waiving author fees in its first years. Also, publication support for authors whose first language is not English will be offered in areas such as manuscript development, English language editing and artwork assistance.

BIOI is now open for submissions; articles can be submitted online at: https://mc04.manuscriptcentral.com/bioi

There are no author submission or article processing fees.

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ISSN 2712-0074

eISSN 2712-0082

Pravinkumar Dinkar Lade and Neelam Singla. Formulation and Development of Tara Gum-mediated Tablets for Delivery of Anticancer Drugs. BIOI. 2024. Vol. 5(1). DOI: 10.15212/bioi-2024-0040